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In problem (P-T), the model variable C โˆˆ โ„ K ร— T could be very large, making the direct solution of (P-T) computationally expensive. Unlike problem (P-S), the problem (P-T) cannot be readily parallelized because the constraints G ( i ) โข ๐’„ i โ‰ฅ 0 couple the entries within each row of C, and the residual term couples entries across columns. Here, we follow the block coordinate-descent approach used in ( Pnevmatikakis et al., 2016 ) and propose an algorithm that sequentially updates each ๐’„ i and ๐’ƒ 0 . For each neuron, we start with a simple unconstrained estimate of ๐’„ i , denoted as ๐’š i ^ , that minimizes the residual of the spatiotemporal data matrix while fixing other neuronsโ€™ spatiotemporal activity and the baseline term ๐’ƒ 0 ,

(9)

where Y res = Y โˆ’ A ^ C ^ โˆ’ b ^ 0 1 T โˆ’ B f represents the residual given the current estimate of the model variables. Due to its unconstrained nature, y ^ i is a noisy estimate of ๐’„ i , plus a constant baseline resulting from inaccurate estimation of ๐’ƒ 0 . Given ๐’š ^ i , various deconvolution algorithms can be applied to obtain the denoised trace ๐’„ ^ i and deconvolved signal ๐’” ^ i ( Vogelstein et al., 2009 ; Pnevmatikakis et al., 2013 ; Deneux et al., 2016 ; Friedrich et al., 2017b ; Jewell and Witten, 2017 ); in CNMF-E, we use the OASIS algorithm from ( Friedrich et al., 2017b ). (Note that the estimation of ๐’„ i is not dependent on accurate estimation of ๐’ƒ 0 , because the algorithm for estimating ๐’„ i will also automatically estimate the baseline term in ๐’š ^ i .) After the ๐’„ i โ€™s are updated, we update ๐’ƒ 0 using the closed-form expression ๐’ƒ ^ 0 = 1 T โข ( Y ~ - A ^ โ‹… C ^ - B ^ f ) โ‹… ๐Ÿ .

Whenever we deal with other developers, but only if thereโ€™s lack of a wider standard, we should at least aim for level 2 consistency, that is, respect their code. We touch something in their domain, we write it like they would do.

When we are in a bigger organization โ€” though "bigger" can truly start at two people โ€” this same idea of level 2 consistency prevails, but we can now think of setting up standards to operate at level 3. There, we can even marry the two levels: Follow the coding guidelines, but when we touch something that violates the guidelines and we donโ€™t have the time to reformat it, we follow the style prevalent in that code.

From my experience, being aware of these levels alone helps a great deal writing more consistent, and with that quite better code.

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, and if you like a short, very short read about them, perhaps also The Little Book of HTML/CSS Coding Guidelines .

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Consistent Design Systems in Sketch With Atomic Design and the Auto-Layout Plugin

Do you design digital products (or websites) and hand design files off to developers for implementation? If you answered yes, settle in! While the should-designers-code debate rages on, we're going to look at how adding a methodology to your design workflow can make you faster, more consistent, and loved byโ€ฆ

March 12, 2018

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Theming With Variables: Globals and Locals

Setting CSS variables to theme a design system can be tricky: if they are too scoped, the system will lose consistency. If they are too global, you lose granularity. Maybe we can fix both issues. Iโ€™d like to try to boil design system variables down to two types: Global andโ€ฆ

March 16, 2018

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Building Maintaining OUI (Optimizely's UI Library): Part 1/2

The following is a guest post by Tom Genoni. Tom is going to introduce us to the thinking and process behind Optimizely's new UI library / Sass framework. Part 2, by Daniel O'Connor, looks at some of the technical and integration bits. When I first started working on web projects,โ€ฆ

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Iโ€™d like to disagree with this if I can. I guess itโ€™s debatable, but it seems like the first step towards forgetting/ignoring the standards completely.

but when we touch something that violates the guidelines and we donโ€™t have the time to reformat it, we follow the style prevalent in that code.

5.2.9. String conversions FORUDESIGNS Women White HighTop Platform Shoes Cute Pet For Sale Buy Authentic Online 6sNQabBSDp

A string conversion is an expression list enclosed in reverse (a.k.a. backward) quotes:

A string conversion evaluates the contained expression list and converts the resulting object into a string according to rules specific to its type.

If the object is a string, a number, , or a tuple, list or dictionary containing only objects whose type is one of these, the resulting string is a valid Python expression which can be passed to the built-in function Factory wholesale 2018 boys stylish casual buckle strap children shoes Classic Cheap Price N3RMgZx
to yield an expression with the same value (or an approximation, if floating point numbers are involved).

(In particular, converting a string adds quotes around it and converts โ€œfunnyโ€ characters to escape sequences that are safe to print.)

Recursive objects (for example, lists or dictionaries that contain a reference to themselves, directly or indirectly) use to indicate a recursive reference, and the result cannot be passed to to get an equal value ( Outlet Eastbay Ladies rhinestone casual shoes crystal beautiful wedding flat shoes Low Shipping Fee Online YR5Kgq01
will be raised instead).

The built-in function performs exactly the same conversion in its argument as enclosing it in parentheses and reverse quotes does. The built-in function performs a similar but more user-friendly conversion.

string_conversion yield_atom yield_expression

New in version 2.5.

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expression in a function definition is sufficient to cause that definition to create a generator function instead of a normal function.

When a generator function is called, it returns an iterator known as a generator. That generator then controls the execution of a generator function. The execution starts when one of the generatorโ€™s methods is called. At that time, the execution proceeds to the first Cheap Outlet Store BaiBeiQi Gladiator Style high heels sandals ladies Sale How Much Buy Online With Paypal Buy Online New Outlet Cost KN3SeZ4i1O
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